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ENSA, Polyclonal, Invitrogen™

Chicken Polyclonal Antibody

Manufacturer:  Invitrogen PA125716

Catalog No. PIPA125716

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.

PA1-25716 detects ENSA from human, mouse, and rat samples.PA1-25716 has been successfully used in Western blot procedures.The PA1-25716 immunogen is full length protein corresponding to residues 1-121 of human ENSA.
Specifications

Specifications

ENSA
Polyclonal
Unconjugated
ENSA
Purified
ENSA
Full length protein corresponding to residues 1-121 of human ENSA.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Murine, Rat
Western Blot
1mg/mL
PBS with no preservative
O43768, P60840, P60841
ARPP-19e, MGC4319, MGC78563, MGC8394
Chicken
IgY
50μg
Store at -20°C
Primary
2029
Documents
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