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ENSA Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527435

Catalog No. PIPA527435


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Description

Description

PA5-27435 targets ENSA in IF and WB applications and shows reactivity with Human samples. The PA5-27435 immunogen is recombit fragment corresponding to a region within amino acids 1 and 121 of Human ENSA. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
Specifications

Specifications

ENSA
Polyclonal
Unconjugated
ENSA
Liquid
ENSA
Recombit fragment corresponding to a region within amino acids 1 and 121 of Human ENSA
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.6 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
O43768, P60840, P60841
ARPP-19e, alpha-endosulfine
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2029, 56205, 60334
Documents
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