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EphB2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA131986

Catalog No. PA131986


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Description

Description

PA1-31986 detects EphB2 from mouse and human samples. PA1-31986 has been successfully used in immunohistochemistry (paraffin tissue), Western blot and ELISA applications. A suggested positive control for this product is mouse heart tissue. The PA1-31986 immunogen is synthetic peptide conjugated to KLH, corresponding to amino acids 118-133 of Human Eph B2. Store at 4°C short term. For extended periods store at -20°C , avoiding freeze/thaw cycles.

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
Specifications

Specifications

EphB2
Polyclonal
Unconjugated
EPHB2
Liquid
EPHB2
Synthetic peptide conjugated to KLH, corresponding to amino acids 118-133 of Human Eph B2.
Protein G
RUO
Antibody
Polyclonal
Human, Mouse
ELISA, Immunohistochemistry (Paraffin), Western Blot
0.25-0.5 mg/mL
PBS with 0.09% sodium azide
P29323, P54763
EPH B2
Rabbit
IgG
400 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
13844, 2048
Documents
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