EphB2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA131986
PA1-31986 detects EphB2 from mouse and human samples. PA1-31986 has been successfully used in immunohistochemistry (paraffin tissue), Western blot and ELISA applications. A suggested positive control for this product is mouse heart tissue. The PA1-31986 immunogen is synthetic peptide conjugated to KLH, corresponding to amino acids 118-133 of Human Eph B2. Store at 4°C short term. For extended periods store at -20°C , avoiding freeze/thaw cycles.Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
|Synthetic peptide conjugated to KLH, corresponding to amino acids 118-133 of Human Eph B2.|
|ELISA, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.09% sodium azide|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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