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EphA2 Rabbit anti-Hamster, Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA514575

Catalog No. PIPA514575


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Description

Description

This antibody is predicted to react with non-human primate based on sequence homology.

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Specifications

Specifications

EphA2
Polyclonal
PBS with 0.09% sodium azide
P29317, Q03145
Ephrin type-A recepor 2; Tyrosine-protein kinase receptor ECK; Epithelial cell kinase
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
100752851, 13836, 1969
Western Blot
Unconjugated
EPHA2
Liquid
EPHA2
KLH conjugated synthetic peptide between 919-950 amino acids from the C-terminal region of human EphA2
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Hamster, Human, Mouse
Documents
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