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EphB3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525975

Catalog No. PIPA525975


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Description

Description

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB3, a member of the Tyr family of protein kinases, is a receptor for members of the ephrin-B family; it binds to both ephrin-B1 and -B2. Expression of this Type I membrane protein is ubiquitous. The protein contains putative domains for 2 fibronectin type III and 1 sterile alpha motif (SAM).
Specifications

Specifications

EphB3
Polyclonal
PBS with 0.09% sodium azide
P54753, P54754
ETK2, HEK2, TYRO6, EK2, EPH-like kinase 2, EPH-like tyrosine kinase 2, EPH-like tyrosine kinase-2, embryonic kinase 2, ephrin type-B receptor 3, human embryo kinase 2, tyrosine-protein kinase TYRO6
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
13845, 2049, 287989
Flow Cytometry, Western Blot
Unconjugated
EPHB3
Liquid
EPHB3
EphB3 his fusion protein.
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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