EphB3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA525975
DescriptionEphrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB3, a member of the Tyr family of protein kinases, is a receptor for members of the ephrin-B family; it binds to both ephrin-B1 and -B2. Expression of this Type I membrane protein is ubiquitous. The protein contains putative domains for 2 fibronectin type III and 1 sterile alpha motif (SAM).
|PBS with 0.09% sodium azide|
|ETK2, HEK2, TYRO6, EK2, EPH-like kinase 2, EPH-like tyrosine kinase 2, EPH-like tyrosine kinase-2, embryonic kinase 2, ephrin type-B receptor 3, human embryo kinase 2, tyrosine-protein kinase TYRO6|
|-20° C, Avoid Freeze/Thaw Cycles|
|13845, 2049, 287989|
|Flow Cytometry, Western Blot|
|EphB3 his fusion protein.|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Human, Mouse, Rat|
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