EPS15, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA146463
EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.Suggested positive control: antigen standard for EPS15 (transient overexpression lysate), Hela whole cell extract.
|Synthetic peptide corresponding to residues 840-896 of the C-terminal portion of human Eps15. [Swiss-Prot# P42566]|
|Antigen affinity chromatography|
|Human, Murine, Rat|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|PBS with 0.1% BSA and 0.04% sodium azide|
|Epidermal growth factor receptor substrate 15 , Protein Eps15 , AF-1p protein , EPS15 , AF1P|
|Store at 4°C short term. For long term storage, Store at -20°C, avoiding freeze/thaw cycles.|
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