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Epstein Barr Virus Nuclear Antigen 1 Goat anti-Virus, Biotin, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA17499

Catalog No. PA17499


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Description

Description

The PA1-7499 antibody reacts with Epstein-Barr virus EBNA-1. PA1-7499 has been successfully used in Immunohistochemical, ELISA, Immunofluorescence and Western blot applications. The PA1-7499 antibody was raised against Recombit EBV EBNA-1. Store at 4°C for up to 6 months. For long term storage, aliquot and freeze at -20°C. Avoid freeze-thaw cycles.

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin ft.s disease and Burkitt ft.s Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all maligcies associated with EBV.
Specifications

Specifications

Epstein Barr Virus Nuclear Antigen 1
Polyclonal
Biotin
Liquid
Goat
IgG
1 mL
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Primary
Virus
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
4-5 mg/mL
PBS with 0.1% sodium azide; pH 7.2
EBV nuclear antigen 1; EBNA-1
Purified recombit EBV EBNA-1.
Purified
RUO
Antibody
Polyclonal
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