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ERAS Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523240

Catalog No. PIPA523240


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Description

Description

The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11.23.
Specifications

Specifications

ERAS
Polyclonal
whole serum with 50% glycerol and 0.025% sodium azide
Q7Z444
HRAS2, HRASP, E-Ras, GTPase ERas, embryonic stem cell-expressed Ras, small GTPase protein E-Ras, v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2, v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Rat
Immunohistochemistry (Paraffin)
Unconjugated
ERAS
Liquid
ERAS
Synthetic peptide (178 VETSAKTRQGVEEAFSLL 195) of ERAS protein.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3266, 679682
Documents
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