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MAPK4 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA514415

Catalog No. PIPA514415

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.
Specifications

Specifications

MAPK4
Polyclonal
PBS with 0.09% sodium azide
P31152, Q6P5G0
Extracellular signal-regulated kinase 4; Mitogen-activated protein kinase 4; ERK-4; MAP kinase isoform p63; p63-MAPK
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
225724, 5596
Immunohistochemistry, Western Blot
Unconjugated
MAPK4
Liquid
MAPK4
KLH conjugated synthetic peptide between 527-557 amino acids from the C-terminal region of human ERK4
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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