Thermo Scientific Lab Vision Estrogen Receptor (SP1), Rabbit Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific Estrogen Receptor (SP1), Rabbit Monoclonal Antibody.
Manufacturer: Thermo Scientific RM9101S0
Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific Estrogen Receptor (SP1), Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Host Species: Rabbit
Species Reactivity: Human, Mouse and Hamster. Others not tested.
Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor
Molecular Weight: 67 kDa
Positive Control: Breast CA, MCF-7 cells
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence (Not verified)
- Flow Cytometery (Not verified)
|Estrogen Receptor (SP1)|
|Synthetic peptide derived from C-terminal of human estrogen receptor|
|Steroids Hormones and Growth Factors|
|Hamster, Human, Murine|
|Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Culture Supernatant with Azide|
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