EVER2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520527
A suggested positive control is rat thymus tissue lysate. PA5-20527 can be used with blocking peptide PEP-0647.Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc.
|An 18 amino acid peptide from near the amino terminus of human EVER2.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|PBS with 0.02% sodium azide|
|EV2, EVER2, EVIN2; epidermodysplasia verruciformis 2; epidermodysplasia verruciformis protein 2; transmembrane channel-like protein 8|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|147138, 217356, 688276|
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