FBXW7 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA123468
PA1-23468 detects F-box hCdc4 in Human samples. PA1-23468 has been successfully used in ELISA and Western Blot procedures. PA1-23468 immunogen corresponds to Rabbit Polyclonal to F - box hCdc4 (69 kDa isoform) Protein. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of maligcies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|ELISA, Western Blot|
|PBS with 0.02% sodium azide|
|Rabbit Polyclonal to F - box hCdc4 (69 kDa isoform) Protein|