F4/80 Rat anti-Mouse, PE, Clone: BM8, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MF48004
EGF-Like Module Containing Mucin-Like Hormone Receptor-Like Sequence 1 (EMR1) is characterized as an Orphan-B GPCR with an unknown ligand. The C-terminus contains seven hydrophobic segments, characteristic of a G protein-coupled receptor. The N-terminus of EMR1 has 6 EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. EMR1 has been reported to be expressed in human peripheral blood mononuclear cells, monocytes, and hematopoietic and solid tumor-derived cell lines. ESTs have been isolated from human normal spleen and mixed liver/spleen libraries and from human kidney, colon, brain, and bone marrow cancer libraries.
|PBS with 10% sucrose, 4mg/mL BSA and 0.1% sodium azide|
|EMR1, EMR1 hormone receptor, F4/80, EGF-like module receptor 1, TM7LN3|
|mouse F4/80 which is a macrophage-restricted cell surface glycoprotein.|
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