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Factor VII Sheep anti-Human, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA143043

Catalog No. PA143043


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Description

Description

PA1-43043 detects Factor VII in human samples. PA1-43043 has successfully been used in Western blot and ELISA applications. PA1-43043 was derived from human factor VII.

Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
Specifications

Specifications

Factor VII
Polyclonal
Unconjugated
F7
Liquid
F7
Human factor VII.
Purified
RUO
Antibody
Polyclonal
Human
ELISA, Western Blot
9.1 mg/mL
50%water with 50% glycerol and no preservative
P08709
F7, Coagulation factor 7
Sheep
IgG
1 mg
-20° C, Avoid Freeze/Thaw Cycles
Primary
2155
Documents
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