Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Factor VIII Sheep anti-Human, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA143045

Catalog No. PA143045


Add to cart

Description

Description

PA1-43045 detects Factor VIII in human samples. PA1-43045 has successfully been used in Western blot and ELISA applications. PA1-43045 was derived from human factor VIII. The molecular weight of PA1-43045 is 150 kDa.

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Specifications

Specifications

Factor VIII
Polyclonal
Unconjugated
F8
Liquid
F8
Human Factor VIII.
Ammonium sulfate precipitation, Ion-exchange chromatography
RUO
Antibody
Polyclonal
Human
ELISA, Western Blot
17.4 mg/mL
50%water with 50% glycerol and no preservative
P00451
F8, HEMA, AHF, Coagulation factor 8
Sheep
IgG
1 mg
-20° C, Avoid Freeze/Thaw Cycles
Primary
2157
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit