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Factor X Rat anti-Mouse, Clone: 9051, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA143036

Catalog No. 01-674-524


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Description

Description

MA1-43036 detects Factor X in mouse samples. MA1-43036 has successfully been used in Western blot and ELISA applications. MA1-43036 was derived from mouse factor X.

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
Specifications

Specifications

Factor X
Monoclonal
Unconjugated
F10
Liquid
F10
Mouse Factor X.
Ammonium sulfate precipitation, Ion-exchange chromatography
RUO
Antibody
Monoclonal
Mouse
ELISA, Western Blot
9051
50%water with 50% glycerol and no preservative
O88947
F10, Coagulation factor 10, Stuart factor
Rat
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
14058
Documents
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