Thermo Scientific Lab Vision Factor XIII A Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific Factor XIII A Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific MS1237P1
Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific Factor XIII A Ab-1, Mouse Monoclonal Antibody.Detect factor XIII in both reduced and non-reduced forms. This abtibody does not react with human Factor XIII B-chain or human Factor XII. Factor XIII is a Β-globulin found in plasma and is composed of two subunits. Factor XIII-A is the catalytic subunit and is a dimer of M.W. 160 kDa. Factor XIII is present in plasma as an alpha2Β2 heterodimer (M.W. 320 kDa); whereas in platelets, only the α2 unit exists. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors. It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system. Factor XIII has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant protein corresponding to A-subunit of coagulation Factor XIII
Molecular Weight: 160 kDa (unreduced dimmer); 80 kDa (reduced monomer)
Positive Control: Recombinant human Factor XIII A-subunit; Capillary hemangioma, dermatofibroma and placenta
Cellular Localization: Cytoplasmic and nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
|Factor XIII A Ab-1|
|Purified Ab with BSA and Azide|
|Immunohistochemistry (Paraffin), Western Blot|
|Recombinant protein corresponding to A-subunit of coagulation Factor XIII|
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