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FAM120A Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520800

Catalog No. PIPA520800

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A suggested positive control is SK-N-SH cell lysate. PA5-20800 can be used with blocking peptide PEP-0914.

FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR -gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells.


An 18 amino acid peptide from near the center of human FAM120A.
Antigen affinity chromatography
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9NZB2, Q6A0A9
C9orf10, DNAPTP1, DNAPTP5, OSSA; DNA polymerase-transactivated protein 1; DNA polymerase-transactivated protein 5; constitutive coactivator of PPAR-gamma-like protein 1; oxidative stress-associated Src activator
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
218236, 23196, 291019
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