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FANCB Mouse anti-Human, Clone: 2B10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA518862

Catalog No. PIMA518862


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Description

Description

Peptide Sequence: GSENFLIDNM AFTLEKELVT LSSLSSAIAK HESNFMQRCE VSKGKSSVVA AALSDRRENI HPYRKELQRE KKKMLQTNLK VSGALYREIT LKVAEVQLKS DFAAQKLSN

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein.
Specifications

Specifications

FANCB
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q8NB91
FANCB
FANCB (NP_689846.1, 750 a.a. ∽ 858 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
ELISA, Western Blot
2B10
Unconjugated
FANCB
Liquid
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
2187
Documents
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