FANCB Mouse anti-Human, Clone: 2B10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA518862
Peptide Sequence: GSENFLIDNM AFTLEKELVT LSSLSSAIAK HESNFMQRCE VSKGKSSVVA AALSDRRENI HPYRKELQRE KKKMLQTNLK VSGALYREIT LKVAEVQLKS DFAAQKLSNThe Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein.
|PBS with no preservative; pH 7.4|
|FANCB (NP_689846.1, 750 a.a. ∽ 858 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
|ELISA, Western Blot|
|-20° C, Avoid Freeze/Thaw Cycles|
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