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CD178 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA121019

Catalog No. PA121019

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

PA1-21041 detects glucose transporter (GLUT1) in human and rat samples. PA1-21041 has been successfully used in immunofluorescenceand immunohistochemistry (paraffin) procedures. Staining of formalin fixed tissues requires boiling tissue sections in 10 mM

Fas ligand (FasL, CD95L) is a type-II-membrane protein, whose N-terminus is in the cytoplasm and its C-terminal region extends into the extracellular space. Its receptor Fas (CD95, Apo-1) is a cell-surface-type-I-membrane protein and a member of the tumor necrosis factor (TNF) and nerve growth factor (NGF) receptor family. As a member of the TNF-cytokine family FasL induces apoptosis when interacting with its receptor Fas. FasL may exist as either membrane bound (45 kD) or soluble forms (26 kD). The soluble protein can be released from cells upon cleavage by metalloproteinases. Binding of FasL to Fas leads to oligomerization of the receptor and triggers apoptotic cell death through the interaction of other proteins. FasL is predomitly expressed in activated T-lymphocytes and natural killer (NK) cells also it is expressed in the tissues of immune-privilege sites such as testis and eye. FasL expression is also reported in various tissues as thymus, liver, ovary, lung, heart and kidney. The Fas/FasL system has been shown to play a role in a number of human diseases, for example AIDS, hepatitis or cancer. It is assumed that induction of apoptosis through FasL is predomitly involved in anti-viral immune responses.
Specifications

Specifications

CD178
Polyclonal
Unconjugated
FASLG
Liquid
Fasl, Faslg
Synthetic peptide (Human) (N-terminal).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin), Western Blot
0.2 mg/mL
PBS with 1% BSA and 0.09% sodium azide; pH 7.4
P48023, P41047, P36940
FasL, apoptosis antigen ligand 1, CD95 ligand, CD95L, CD178, APO1, Fas Ligand, Fas-LG
Rabbit
IgG
500 μL
4° C, do not freeze
Primary
14103, 25385, 356
Documents
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