FceR1 alpha, FITC, clone: CRA2 (AER24), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA15025

Catalog No. PIMA15025

Description

Fc epsilonR1 alpha is a subunit of the high affinity receptor of IgE to which it directly binds. Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one β and two additional subunits. The latter two are required for signal transduction activity. The Fc epsilonR1 complex plays an important role in triggering allergic responses.

MA1-5025 detects Fc epsilonR1 alpha (FITC) from human samples. The CRA2 (AER24) monoclonal antibody reacts with the Fc epsilonR1 alpha subunit on a region that overlaps the region of the IgE binding site, thus it competes with IgE for the receptor bindingMA1-5025 has been successfully used in immunocytochemistry, flow cytometry, and immunohistochemistry applications.The MA1-5025 immunogen is region of Fc epsilonR1 alpha which overlaps with the IgE binding site.

Specifications

• Antigen: Fc epsilon R1 alpha
• Classification: Monoclonal
• Concentration: 1mg/mL
• Gene: FCER1A
• Gene Alias: RP11-550P17.3, FCE1A, FcERI
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 2205
• Content And Storage: Store at -20°C, Avoid Freeze/Thaw Cycles
• Form: Purified

• Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry
• Clone: CRA2 (AER24)
• Conjugate: FITC
• Gene Accession No.: P12319
• Gene Symbols: FCER1A
• Immunogen: Region of Fc epsilonR1 alpha which overlaps with the IgE binding site.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ