FER Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA522992
This antibody is predicted to react with mouse and canine based on 100% sequence homology. Suggested positive control: Jurkat whole cell lysate.Protein kinases constitute a large superfamily of enzymes with key regulatory functions in nearly all signal transmission processes of eukaryotic cells (1). FER is found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes (2). The group IV cytoplasmic protein-tyrosine kinase Fer has been linked to cellular signaling responses to many different stimuli, including growth factors and cytokines. Data suggest a biological role for Fer in regulation of leukocyte recruitment during the innate immune response (3).
|Synthetic peptide made to an internal portion of the human protein (within residues 400-450).|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 30% glycerol and 0.1% sodium azide|
|PPP1R74, TYK3, feline encephalitis virus-related kinase FER, fujinami poultry sarcoma/Feline sarcoma-related protein Fer, p94-Fer, phosphoprotein NCP94, protein phosphatase 1, regulatory subunit 74, proto-oncogene c-Fer, tyrosine kinase 3, tyrosine-protein kinase Fer|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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