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FEZ2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520456

Catalog No. PIPA520456


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Description

Description

A suggested positive control is mouse brain tissue lysate. PA5-20456 can be used with blocking peptide PEP-0573.

Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
Specifications

Specifications

FEZ2
Polyclonal
Unconjugated
FEZ2
Liquid
FEZ2
A 15 amino acid peptide from near the carboxy terminus of human FEZ2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9UHY8, Q6TYB5, P97578
HUM3CL; fasciculation and elongation protein zeta-2; pre-T/NK cell associated protein (3Cl); zygin 2; zygin II; zygin-2
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
225020, 94269, 9637
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