FGF4 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA515464

Catalog No. PIPA515464

Description

FGF4 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The gene for FGF4 was identified by its oncogenic transforming activity. The gene for FGF4 and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

Specifications

• Antigen: FGF4
• Classification: Polyclonal
• Gene: FGF4
• Gene Alias: Fibroblast growth factor-4; FGF-4; Heparin secretory transforming protein; HST-1; HST; Transforming protein KS3; HBGF-4
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 2249
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: P08620
• Gene Symbols: FGF4
• Immunogen: KLH conjugated synthetic peptide between 168-198 amino acids from the C-terminal region of human FGF4
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG