FGFR2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA514653

Catalog No. PIPA514653

Description

This antibody is predicted to react with mouse based on sequence homology.

FGFR2 is a member of the fibroblast growth factor receptor family. It is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a central role in the regulation of cell proliferation, differentiation, migration, apoptosis, and embryonic development. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Specifications

• Antigen: FGFR2
• Classification: Polyclonal
• Gene: FGFR2
• Gene Alias: Fibroblast Growth Factor Receptor 2, BEK, BFR-1, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, CD332, FGF Receptor 2
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 2263
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: P21802
• Gene Symbols: FGFR2
• Immunogen: KLH conjugated synthetic peptide between 7-37 amino acids from the N-terminal region of human FGFR2
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG