FGR Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527140
PA5-27140 targets FGR in WB applications and shows reactivity with Human samples. The PA5-27140 immunogen is synthetic peptide corresponding to a region within amino acids 467 and 529 of Human FGR. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
|Synthetic peptide corresponding to a region within amino acids 467 and 529 of Human FGR|
|Antigen affinity chromatography|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|SRC2, c-fgr, c-src2, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr, c-fgr protooncogene, c-src-2 proto-oncogene, p55-c-fgr protein, proto-oncogene c-Fgr, proto-oncogene tyrosine-protein kinase FGR, tyrosine-protein kinase Fgr|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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