Fibrinogen Chicken anti-Human, Polyclonal, Invitrogen™
Chicken Polyclonal Antibody
Manufacturer: Invitrogen PA19526
PA1-9526 detects Fibrinogen in human samples. PA1-9526 has been successfully used in Western blot and ELISA procedures. By Western blot, PA1-9526 detects a ∽94 kDa protein representing Fibrinogen. The PA1-9526 immunogen is a mixture of synthetic peptides based on human fibrinogen.Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
|Mixture of synthetic peptides based on human fibrinogen.|
|ELISA, Western Blot|
|PBS with 0.02% sodium azide|
|FGA, Fib2, Fibrinogen A alpha polypeptide chain, Fibrinogen alpha chain|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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