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FKBP25 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528275

Catalog No. PIPA528275


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Description

Description

PA5-28275 targets FKBP25 in WB applications and shows reactivity with Human and mouse samples. The PA5-28275 immunogen is recombit fragment corresponding to a region within amino acids 2 and 224 of Human FKBP25. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Specifications

Specifications

FKBP25
Polyclonal
Unconjugated
FKBP3
Liquid
FKBP3
Recombit fragment corresponding to a region within amino acids 2 and 224 of Human FKBP25
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
0.53 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Q00688, Q62446
FKBP-25, FKBP-3, FKBP25, PPIase, 25 kDa FK506-binding protein, 25 kDa FKBP, FK506-binding protein 25, T-cell, FK506-binding protein 3 (25kD), PPIase FKBP3, immunophilin FKBP25, peptidyl-prolyl cis-trans isomerase FKBP3, rapamycin binding protein, rapamycin-selective 25 kDa immunophilin, rotamase
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2287, 30795
Documents
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