FKBP25 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528275
PA5-28275 targets FKBP25 in WB applications and shows reactivity with Human and mouse samples. The PA5-28275 immunogen is recombit fragment corresponding to a region within amino acids 2 and 224 of Human FKBP25. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
|Recombit fragment corresponding to a region within amino acids 2 and 224 of Human FKBP25|
|Antigen affinity chromatography|
|0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7|
|FKBP-25, FKBP-3, FKBP25, PPIase, 25 kDa FK506-binding protein, 25 kDa FKBP, FK506-binding protein 25, T-cell, FK506-binding protein 3 (25kD), PPIase FKBP3, immunophilin FKBP25, peptidyl-prolyl cis-trans isomerase FKBP3, rapamycin binding protein, rapamycin-selective 25 kDa immunophilin, rotamase|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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