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FLT3, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA514668

Catalog No. PIPA514668

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

Specifications

Specifications

FLT3
Polyclonal
PBS with 0.09% sodium azide
P36888
Tyrosine-protein kinase receptor FLT3, STK1, FL cytokine receptor, Stem cell tyrosine kinase 1, CD135 antigen
Rabbit
IgG
400μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2322
Immunohistochemistry, Western Blot
Unconjugated
FLT3
Liquid
FLT3
KLH conjugated synthetic peptide between 951-982 amino acids from the C-terminal region of human FLT3 (CD135)
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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