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FMRP Mouse anti-Drosophila, Clone: 6A15, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA15771

Catalog No. 01-674-887


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Description

Description

MA1-5771 detects FMR1 in drosophila samples (does not cross react with human). MA1-5771 has been successfully used in Western blot, immunoprecipitation, immunofluorescence and ELISA procedures. MA15771 detects a band of approximately 85 kDa. The MA1-5771 immunogen is His-dFMR1 (amino-terminal 580a.a.). Store product at 4°C for up to one month, and -20°C for up to one year.

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5 ft. UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure . Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Specifications

Specifications

FMRP
Monoclonal
1 mg/mL
PBS with 0.1% sodium azide
Q9NFU0
FMRP, FRAXA, MGC87458
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
37528
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
6A15
Unconjugated
Fmr1
Liquid
FMR1
His-dFMR1 (amino-terminal 580 a.a.) from SP2/0 cells
Protein A
RUO
Antibody
Monoclonal
Drosophila
Documents
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