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FMRP Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA529661

Catalog No. PIPA529661


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Description

Description

PA5-29661 targets FMRP in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-29661 immunogen is a recombit fragment corresponding to a region within amino acids 85 and 300 of FMRP.

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5 ft. UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1).
Specifications

Specifications

FMRP
Polyclonal
Unconjugated
FMR1
Liquid
FMR1
Recombit fragment contain a sequence corresponding to a region within amino acids 85 and 300 of FMRP
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q06787, Q80WE1
FMRP, FRAXA, POF, POF1, fragile X mental retardation 1 protein, fragile X mental retardation protein 1, protein FMR-1
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2332, 24948
Documents
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