FMRP Rabbit anti-Human, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA529661
PA5-29661 targets FMRP in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-29661 immunogen is a recombit fragment corresponding to a region within amino acids 85 and 300 of FMRP.The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5 ft. UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1).
|Recombit fragment contain a sequence corresponding to a region within amino acids 85 and 300 of FMRP|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|FMRP, FRAXA, POF, POF1, fragile X mental retardation 1 protein, fragile X mental retardation protein 1, protein FMR-1|
|-20° C, Avoid Freeze/Thaw Cycles|
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