FOXC1 Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523160
DescriptionFOXC1 is a protein belonging to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this protein is not known, however, it plays a role in the regulation of FGF19-FGFR4-MAPK pathway to promote both the development and maintece of anterior segment structures within the eye. Mutations in this gene cause various glaucoma, iridogoniodysgenesis anomaly, Peters anomaly that includes central corneal leukoma, absence of the posterior corneal stroma and Descemetmembrane and Axenfeld-Rieger anomaly characterized by posterior corneal embryotoxon, iris adhesion to the Schwalbe line, hypertelorism, hypoplasia of the malar bones, congenital absence of some teeth and mental retardation.
|whole serum diluted in PBS with 0.2% gelatin and 0.05% sodium azide|
|ARA, FKHL7, FREAC-3, FREAC3, IGDA, IHG1, IRID1, RIEG3, forkhead box protein C1, forkhead, drosophila, homolog-like 7, forkhead-related activator 3, forkhead-related protein FKHL7, forkhead-related transcription factor 3, forkhead/winged helix-like transcription factor 7, myeloid factor-delta|
|Human, Non-human Primate|
|Immunohistochemistry (Paraffin), Western Blot|
|Synthetic peptide (279 SARPLSLDGADSAP 292) of FOXC1 protein.|
|-20° C, Avoid Freeze/Thaw Cycles|
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