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FOXO3A Rabbit anti-Bovine, Canine, Chicken, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523191

Catalog No. PIPA523191


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Description

Description

FOXO3A belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. FOXO3A is an embryonic transcriptional regulator involved in erythropoiesis and plays an important role in the cell cycle of megakaryocytic cells. It also has a critical role in regulation of proliferation, control of oxidative stress and triggers apoptosis by inducing the expression of genes such as the Fas ligand gene TNFSF6. It is also known to regulate cardiac myocyte size downstream of AKT signaling. FOXO3A promotes DNA repair under low stress conditions and a program of cell death under higher level of stress thus protecting quiescent cells from oxidative stress.
Specifications

Specifications

FOXO3A
Polyclonal
Unconjugated
FOXO3
Liquid
FOXO3
Synthetic peptide (661 GAKQASSQSWVPG 673) of FOXO3A/FKHRL1 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Canine, Chicken, Human, Mouse, Non-human primate, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
O43524, Q9WVH4
AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, forkhead box O3A, forkhead box protein O3, forkhead homolog (rhabdomyosarcoma) like 1, forkhead in rhabdomyosarcoma-like 1, forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2309, 294515, 421769, 481954, 535530, 56484
Documents
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