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FOXP2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525656

Catalog No. PIPA525656


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Description

Description

This antibody is predicted to react with rat based on sequence homology.

FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal domit speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.
Specifications

Specifications

FOXP2
Polyclonal
PBS with 0.09% sodium azide
O15409, P58463
CAGH44, SPCH1, TNRC10, CAG repeat protein 44, forkhead box protein P2, forkhead/winged-helix transcription factor, trinucleotide repeat containing 10, trinucleotide repeat-containing gene 10 protein
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
114142, 93986
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
FOXP2
Liquid
FOXP2
KLH conjugated synthetic peptide between 657-684 amino acids from the C-terminal region of human FOXP2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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