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FREM2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520982

Catalog No. PIPA520982


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Description

Description

A suggested positive control is A-20 cell lysate. PA5-20982 can be used with blocking peptide PEP-1096.

FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
Specifications

Specifications

FREM2
Polyclonal
Unconjugated
FREM2
Liquid
FREM2
A 19 amino acid peptide near the center of human FREM2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q5SZK8, Q6NVD0
ECM3 homolog; FRAS1-related extracellular matrix protein 2
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
242022, 341640
Documents
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