FVT1 Mouse anti-Human, Clone: 2B2-3C11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA518923
Peptide Sequence: FVLLLYMVSP LISPKPLALP GAHVVVTGGS SGIGKCIAIE CYKQGAFITL VARNEDKLLQ AKKEIEMHSI NDKQVVLCIS VDVSQDYNQV ENVIKQAQEK LGPVDMLVNC AGMAVSGKFE DLEVSTFERL MSINYLGSVY PSRAVITTMK ERRVGRIVFV SSQAGQLGLF GFTAYSASKF AIRGLAEALQ MEVKPYNVYI TVAYPPDTDT PGFAEENRTK PLETRLISET TSVCKPEQVA KQIVKDAIQG NFNSSLGSDG YMLSALTCGM APVTSITEGL QQVVTMGLFR TIALFYLGSF DSIVRRCMMQ REKSENADKT AThe protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
|PBS with no preservative; pH 7.4|
|DHSR, FVT1, SDR35C1, 3-dehydrosphinganine reductase, FVT-1, KDS reductase, follicular lymphoma variant translocation 1, follicular variant translocation protein 1, short chain dehydrogenase/reductase family 35C, member 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|KDSR (AAH08797.1, 12 a.a. ∽ 332 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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