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FVT1 Mouse anti-Human, Clone: 2B2-3C11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA518923

Catalog No. PIMA518923


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Description

Description

Peptide Sequence: FVLLLYMVSP LISPKPLALP GAHVVVTGGS SGIGKCIAIE CYKQGAFITL VARNEDKLLQ AKKEIEMHSI NDKQVVLCIS VDVSQDYNQV ENVIKQAQEK LGPVDMLVNC AGMAVSGKFE DLEVSTFERL MSINYLGSVY PSRAVITTMK ERRVGRIVFV SSQAGQLGLF GFTAYSASKF AIRGLAEALQ MEVKPYNVYI TVAYPPDTDT PGFAEENRTK PLETRLISET TSVCKPEQVA KQIVKDAIQG NFNSSLGSDG YMLSALTCGM APVTSITEGL QQVVTMGLFR TIALFYLGSF DSIVRRCMMQ REKSENADKT A

The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
Specifications

Specifications

FVT1
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q06136
DHSR, FVT1, SDR35C1, 3-dehydrosphinganine reductase, FVT-1, KDS reductase, follicular lymphoma variant translocation 1, follicular variant translocation protein 1, short chain dehydrogenase/reductase family 35C, member 1
Mouse
IgG1, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
2531
ELISA, Western Blot
2B2-3C11
Unconjugated
KDSR
Liquid
KDSR
KDSR (AAH08797.1, 12 a.a. ∽ 332 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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