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FXR Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1334

Catalog No. PA1334


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Description

Description

PA1-334 detects FXR in mouse samples. PA1-334 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~55 kDa protein representing FXR in mouse liver samples. An unknown band at ~60 kDa is also observed in western blots. The PA1-334 immunogen is a synthetic peptide corresponding to residues R(224) K N V K Q H A D Q T V N E D(238) of mouse FXR. The PA1-334 immunizing peptide (Cat. No. PEP-273) is available for use in neutralization and control experiments.

Farnesoid X-activated receptor (FXR), also known as the Bile acid receptor, is a member of the nuclear hormone receptor superfamily. FXR is involved in the regulation of bile acid metabolism. FXR forms a heterodimeric complex with the retinoic X receptor in the presence of a ligand. FXR is expressed primarily in liver and kidney. The corresponding gene for the FXR is NR1H4.
Specifications

Specifications

FXR
Polyclonal
Unconjugated
Nr1h4
Liquid
NR1H4
Synthetic peptide corresponding to residues R(224) K N V K Q H A D Q T V N E D(238) of mouse FXR.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Mouse
Western Blot
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
Q60641
Nr1h4, Bile acid receptor, Farnesoid X-activated receptor, Farnesol receptor HRR-1, Retinoid X receptor-interacting protein 14, RXR-interacting protei
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
20186
Documents
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