Fyn Mouse anti-Human, Mouse, Rat, Clone: 1S, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112607
This antibody recognizes epitope aa 26-75. Staining of formalin-fixed paraffin embedded tissue sections requires boiling the sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at room temperature for 20 minutes.Fyn is a membrane-associated non-receptor protein tyrosine kinase that belongs to the Src-family of kinases. The unique N-terminal domain of Fyn interacts with the CD3 and Delta chains of the TcR. p59 fyn can bind other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of Fyn activity. Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.
|PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4|
|P06241, P39688, Q62844|
|Tyrosine-protein kinase Fyn, Proto-oncogene Syn, Proto-oncogene c-Fyn, Src-like kinase, SLK, p59-Fyn, FYN|
|4° C, Avoid Freeze/Thaw Cycles|
|14360, 25150, 2534|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Recombit protein corresponding to amino acid residues 1-206 of murine p59fynprotein.|
|Human, Mouse, Rat|
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