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FZD6 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA524488

Catalog No. PIPA524488

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with mouse based on sequence homology.

This gene represents a member of the  ft.frizzled ft. gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
Specifications

Specifications

FZD6
Polyclonal
PBS with 0.09% sodium azide
O60353
FZ-6, FZ6, HFZ6, NDNC10, frizzled 6, seven transmembrane spanning receptor, frizzled homolog 6, frizzled-6, seven transmembrane helix receptor
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8323
Western Blot
Unconjugated
FZD6
Liquid
FZD6
KLH conjugated synthetic peptide between 493-520 amino acids from the central region of human FZD6
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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