FZD6 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA524488
This antibody is predicted to react with mouse based on sequence homology.This gene represents a member of the ft.frizzled ft. gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
|PBS with 0.09% sodium azide|
|FZ-6, FZ6, HFZ6, NDNC10, frizzled 6, seven transmembrane spanning receptor, frizzled homolog 6, frizzled-6, seven transmembrane helix receptor|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 493-520 amino acids from the central region of human FZD6|
|Antigen affinity chromatography|
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