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FZD7 Rat anti-Human, Mouse, Clone: 151143, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA524378

Catalog No. PIMA524378


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Description

Description

In direct ELISAs, no cross-reactivity with recombit mouse Frizzled-1, -3, -4 or -8 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Members of the  ft.frizzled ft. gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Specifications

Specifications

FZD7
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
O75084, Q61090
FZD7, Frizzled family receptor 7, Frizzled homolog 7, Frizzled 7, Frizzled-7, FzE3, Fz-7, HFz7
Rat
IgG2A
50 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
14369, 8324
Flow Cytometry, Immunocytochemistry, Immunofluorescence
151143
Unconjugated
FZD7
Lyophilized
FZD7
Mouse myeloma cell line NS0-derived recombit mouse Frizzled-7 Gln33-Leu185
Protein A/G
RUO
Antibody
Monoclonal
Human, Mouse
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