Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

anti-Gαo G-Protein Ab-2, Clone: 2A.3, Thermo Scientific Lab Vision

Mouse Monoclonal Antibody

Specifications

Antigen Gαo G-Protein Ab-2
Format Purified
Host Species Murine
Immunogen Partially purified bovine brain Gαo protein
Isotype IgG1
View More Specs

Products 6
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS242P
View Documents
Epredia
MS242P
200μg/mL Unconjugated 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS242P1
View Documents
Epredia
MS242P1
200μg/mL Unconjugated 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS242P0
View Documents
Epredia
MS242P0
200μg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS242P1ABX
View Documents
Epredia
MS242P1ABX
1mg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS242PABX
View Documents
Epredia
MS242PABX
1mg/mL Unconjugated 200μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS242PCL
View Documents
Epredia
MS242PCL
250μg/100μL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Go belongs to the pertussis toxin sensitive G-proteins. It consists of two subtypes of α-subunits (αo1 and αo2) derived from alternative splicing of a single gene. αo1 differs from αo2 within the C-terminal third of the deduced amino acid sequence.

Host Species: Mouse
Clone: 2A.3
Isotype: IgG1
Cross Reactivity: Human, Cow, Rat, Mouse, and Guinea pig. Others-not known
Epitope: Not determined
Immunogen: Partially purified bovine brain Gαo protein
Molecular Weight: 39-42kDa
Positive Control: IMR-5 cells. Brain
Cellular Localization: Cell membrane

Ab-2 is highly specific to Galphao and shows no cross-reaction with transducin, Gαi1, Gαi2, Gαi3, or Gαs. It reacts equally with the C-terminal splice variants of Gαo (mouse GαoA and GαoB, equivalent to Gαo1 and Gαo2 in other species).

Western Blotting

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Specifications

Gαo G-Protein Ab-2
Murine
IgG1
Primary
Purified
Partially purified bovine brain Gαo protein
Monoclonal
SDS
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit