GPR109B Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141622
PA1-41622 detects GPR109B in chimpanzee and human samples. This antibody is predicted to react with canine and hamster based on sequence homology.GPR109B is a membrane protein belonging to family 1 of G protein-coupled receptor (GPCR) is homologous to GPR109A. GPR109B, a potential 7 transmembrane-spanning receptor, shows a significant homology to B2 bradykinin receptor and to thrombin receptor. GPR109B mediates the anti-lipolytic and lipid-lowering effect of nicotinic acid by acting as a nicotinic acid receptor and results in a G protein-mediated decrease in cAMP levels and hence are promising targets for future pharmacotherapy. It is known to show highest expression in spleen followed by lymphocytes and adipose tissue.
|Synthetic peptide corresponding to residues 1-50 of human GPR109B.|
|Antigen affinity chromatography|
|Human, Non-human Primate|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.2% gelatin and 0.05% sodium azide|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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