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CRTH2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14190

Catalog No. PA14190


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Description

Description

PA1-4190 detects GPR44 from human, mouse and rat samples. PA1-4190 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~66 kDa protein representing GPR44 in GPR44 transfected Jurkat cells. The PA1-4190 immunogen is a synthetic peptide corresponding to residues D(329) D S E L G G A G S S R R R R T S S T A(348) of human G Protein-Coupled Receptor GPR44.

CRTH2 (chemoattractant receptor-homologous molecule), which is also known as the putative G protein-coupled receptor (GPR44), is expressed on Th2 cells and is a novel member of the G protein-coupled leukocyte chemoattractant receptor family, which is selectively expressed in Th2 but not Th1 lineage cells. CRTH2 is selectively expressed in vivo in an activated state of Th2 cells including allergen-responsive Th2 cells, suggesting its pivotal roles in ongoing Th2-type immune reactions.
Specifications

Specifications

CRTH2
Polyclonal
Unconjugated
PTGDR2
Liquid
PTGDR, PTGDR2
Synthetic peptide corresponding to residues D(329) D S E L G G A G S S R R R R T S S T A(348) of human G Protein-Coupled Receptor GPR44.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q13258, Q9Y5Y4, P70263, Q9Z2J6, Q6XKD3, Q9R261
CD294, CRTH2, DL1R, DP2, GPR44, G protein-coupled receptor 44, G Protein-Coupled Rec. 44
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
11251, 14764, 19214, 309212, 498475, 5729
Documents
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