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GPR77 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141397

Catalog No. 01-675-526


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Description

Description

This antibody is predicted to react with bovine and rhesus monkey samples based on sequence homology. Suggested positive control: antigen standard for GPR77 (transient overexpression lysate), human testis cell lysate, human testis protein.

Principal Names: G-protein coupled receptor 77 (GPCR77); C5a anaphylatoxin chemotactic receptor C5L2; GPF77; Official Gene Symbol: GPR77 Gen Bank Accession Number: NP_060955 Gene ID: 27202 (human) Gene Map Locus: 19q13.33 (human) C5L2 is 337A.A orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.
Specifications

Specifications

GPR77
Polyclonal
Unconjugated
C5AR2
Liquid
C5AR2
Synthetic peptide corresponding to residues 1-50 of human GPR77.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.05% sodium azide
Q9P296
GPR77, C5L2
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
27202
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