G6PD, Mouse, Clone: 3H5, Abnova
Mouse monoclonal antibody raised against a partial recombinant G6PD.
Manufacturer: Abnova Corporation H00002539M01
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic nonspherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeqSequence: TKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
|G6PD (AAH00337, 406 a.a. ∽515 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26KDa.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|In 1X PBS, pH 7.4|