G6PD, Mouse, Clone: 3H5, Abnova™

Mouse monoclonal antibody raised against a partial recombinant G6PD.

Manufacturer: Abnova Corporation H00002539M01A

Catalog No. 89-022-246

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    Format Ascites
    Formulation In ascites fluid
    Gene G6PD
    Gene Accession No. BC000337
    Gene Alias G6PD1
    Gene Symbols G6PD
    Applications Enzyme Linked Immunosorbent Assay
    Regulatory Status RUO
    Species Reactivity Human
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Gene ID (Entrez) 2539
    Description glucose-6-phosphate dehydrogenase
    Antigen G6PD
    Host Species Mouse
    Immunogen G6PD (AAH00337, 406 a.a. ∽515 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26KDa.
    Isotype IgG2a, κ
    Quantity 200μL
    Primary or Secondary Primary
    Monoclonal or Polyclonal Monoclonal
    Clone 3H5
    Conjugate Unlabeled
    Cross Reactivity Human

    This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic nonspherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq


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