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G6PD Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527359

Catalog No. PIPA527359


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Description

Description

PA5-27359 targets G6PD in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27359 immunogen is recombit fragment corresponding to a region within amino acids 237 and 508 of Human G6PD. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

G6PD
Polyclonal
Unconjugated
G6PD
Liquid
G6PD, G6pdx
Recombit fragment corresponding to a region within amino acids 237 and 508 of Human G6PD
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.81 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q00612, P11413
G6PD1, glucose-6-phosphate 1-dehydrogenase, glucose-6-phosphate dehydrogenase, G6PD
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
14381, 2539
Documents
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