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GABRA1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527985

Catalog No. PIPA527985


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Description

Description

PA5-27985 targets GABA A Receptor alpha 1 in WB applications and shows reactivity with Human samples. The PA5-27985 immunogen is recombit fragment corresponding to a region within amino acids 1 and 261 of Human GABA A Receptor alpha 1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
Specifications

Specifications

GABRA1
Polyclonal
Unconjugated
GABRA1
Liquid
GABRA1
Recombit fragment corresponding to a region within amino acids 1 and 261 of Human GABA A Receptor alpha 1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
0.75 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P14867
ECA4, EJM, EJM5, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2554
Documents
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