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GALNT4 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523699

Catalog No. PIPA523699


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Description

Description

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon.
Specifications

Specifications

GALNT4
Polyclonal
Unconjugated
GALNT4
Liquid
GALNT4
KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human GALNT4
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Flow Cytometry, Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
Q8N4A0
GALNAC-T4, GALNACT4, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4, polypeptide GalNAc transferase 4, polypeptide N-acetylgalactosaminyltransferase 4, pp-GaNTase 4, protein-UDP acetylgalactosaminyltransferase 4
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8693
Documents
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