gamma Synuclein Sheep anti-Human, Rat, Polyclonal, Invitrogen
Sheep Polyclonal Antibody
Manufacturer: Invitrogen PA118262
Reconstitute with 20 µL of distilled water.Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer ft.s (AD), Parkinson ft.s PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.
|Synthetic peptide corresponding to residues E(114) K E E V A E E A Q S G G D(127) of human gamma synuclein protein.|
|Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Persyn, Breast cancer-specific gene 1 protein, Synoretin, SR|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.|
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